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The homocysteine-inducible, endoplasmic reticulum (ER) stress-inducible, ubiquitin-like domain member 2 (HERPUD1) in cultured HELA cells facilitate cytoprotective effects against oxidative stress by suppressing the inositol 1,4,5-triphosphate receptor and reducing the transfer of calcium ions from the endoplasmic reticulum to mitochondria [41]

Metabolites were identified based on the instruments resolution settings and RT, referenced against an in-house library of chemical standards

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Free radicals are unstable molecules that can originate from environmental factors like pollution and toxins, as well as natural processes such as metabolism